Archive for the ‘Life Science’ Category

Flow Cytometry Part 3: Improving Signal-to-Noise Ratio in Flow Cytometer Optics

Key Takeaways: Flow cytometry is a method for studying cells using fluorescent tagging and optical analysis as they flow past a laser. Improving the signal-to-noise ratio (SNR) is essential in flow cytometry for reducing background noise and enhancing relevant cell signals, achieved through optimizing optical components. Laser performance directly affects SNR, with stable output power […]

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Understanding Key Optical Techniques: Fluorescence-Lifetime Imaging

Key Takeaways FLIM Advances Diagnostics: FLIM offers precise views of living cells and proteins, aiding diagnoses and enhancing understanding of diseases like cancer. TCSPC Measures Fluorescence Lifetimes: TCSPC captures differences in fluorescence lifetime, enabling picosecond-level measurements crucial for medical imaging. FRET Enhances Protein Studies: FRET microscopy, combined with FLIM, provides detailed insights into protein interactions, […]

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Case Study: Two-Aspheric Cemented Lenses for Enhanced Image Clarity in Ophthalmic Examinations

       Key Takeaways Avantier manufactures a two-aspheric cemented lens by combining two aspheric lenses, which corrects aberrations and enhances optical performance.  Specifically designed for innovative eyepieces in ophthalmic examinations, these lenses excel in minimizing distortions to improve image quality and clarity, making them suitable for various fields.  The project focused on achieving high […]

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Case Study: High and Low Temperature Resistant 25X Objective Lens: High Imaging Quality & High-Resolution Performance

        Key Takeaways Avantier’s project introduces a custom-designed 25X objective lens for Isotope Ratio Mass Spectrometer systems, specifically tailored for researching isotopes. Operating on the principle of charged particles deflected in an electromagnetic field, the lens facilitates precise substance separation and detection based on mass differences, enabling detailed composition analysis. Ensuring high […]

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Live-Cell Imaging with Advanced Microscope Technology

     Key Takeaways Live-cell imaging is revolutionizing cellular biology, offering insights into cellular behavior, developmental stages, and drug impact. This method visualizes individual or collective cell movements, morphological changes, and gene/protein expression under a microscope, all while keeping the cells alive.  The significance of live-cell imaging  is in its capacity to provide direct, real-time […]

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Case Study – 20X Objective Lens & Tube Lens For Observing Blood

     Key Takeaways This medical research project employs a 20X lens from Avantier for deep exploration of single-cell genetic expression and for immune profiling in human blood cells under a microscope.  The high magnification enables meticulous analysis, unveiling insights into genetic patterns, immune responses, and chromatin accessibility. This contributes to the advancement of  single-cell […]

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Case Study: High NA Objective Lens

Case Study:High NA Objective Lens Avantier’s Innovative Approach to Custom High NA Objective for Microscope Manufacturer Avantier, a custom optic company, addressed a microscope manufacturer’s challenge by developing a custom high NA long working distance objective. Their innovative approach included the use of a Fused Silica chamber filled with liquid instead of a traditional block […]

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Case Study – Fisheye Lenses

     Key Takeaways A scientific institute faced distortion and chromatic aberration issues in high-performance lenses, affecting image quality and accuracy for scientific observation. Avantier crafted a fisheye lens with controlled F-θ distortion (<2%) and chromatic aberration (<0.04mm). The lens ensured accurate target acquisition and maintained high image quality, eliminating the need for distortion correction. […]

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How Small Objective Lenses Are Used in Our Lives?

     Key Takeaways The compact Small Objective Lens transforms medical imaging with sterile, high-definition precision for diagnostics and interventions. Its small size navigates intricate anatomical structures, aiding comprehensive examinations in endoscopes or microscopes. Designed for sterility, it enhances patient safety in invasive procedures, reducing the risk of complications. Delivering unparalleled detail, the lens is […]

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Telescopes: Optics, Mechanics, and Customization

Telescopes: Optics, Mechanics, and Customization Telescopes, based on the principle of angular magnification, enable viewers to observe distant objects by enlarging their angular fields. This involves pairing optical elements with specific powers to modify the angular field. Despite the apparent complexity, the concept is straightforward, simplifying the construction of telescopes. How Do Telescopes Work? Telescopes, […]

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